Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells
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چکیده
منابع مشابه
Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells
BACKGROUND We present the potential of inclusion bodies (IBs) as a protein delivery method for polymeric filamentous proteins. We used as cell factory a strain of E. coli, a conventional host organism, and keratin 14 (K14) as an example of a complex protein. Keratins build the intermediate filament cytoskeleton of all epithelial cells. In order to build filaments, monomeric K14 needs first to d...
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ژورنال
عنوان ژورنال: Microbial Cell Factories
سال: 2012
ISSN: 1475-2859
DOI: 10.1186/1475-2859-11-67